diff --git a/Content.IntegrationTests/Tests/Body/DetachableOrganSystemTest.cs b/Content.IntegrationTests/Tests/Body/DetachableOrganSystemTest.cs
new file mode 100644
index 0000000000..67d210ccf8
--- /dev/null
+++ b/Content.IntegrationTests/Tests/Body/DetachableOrganSystemTest.cs
@@ -0,0 +1,111 @@
+using System.Linq;
+using Content.IntegrationTests.Fixtures;
+using Content.IntegrationTests.Fixtures.Attributes;
+using Content.Shared.Body;
+using Robust.Shared.Containers;
+using Robust.Shared.GameObjects;
+using Robust.Shared.Map;
+
+namespace Content.IntegrationTests.Tests.Body;
+
+[TestFixture]
+[TestOf(typeof(DetachableOrganSystem))]
+public sealed class DetachableOrganSystemTest : GameTest
+{
+    private const string DetachTestOldBody = "DetachTestOldBody";
+    private const string DetachTestNewBody = "DetachTestNewBody";
+    private const string DetachTestGrandParentOrgan = "DetachTestGrandParentOrgan";
+    private const string DetachTestRootOrgan = "DetachTestRootOrgan";
+    private const string DetachTestChildOrgan = "DetachTestChildOrgan";
+    private const string DetachTestSiblingOrgan = "DetachTestSiblingOrgan";
+
+    [TestPrototypes]
+    private const string Prototypes = $@"
+- type: entity
+  id: {DetachTestOldBody}
+  components:
+  - type: Body
+
+- type: entity
+  id: {DetachTestNewBody}
+  components:
+  - type: Body
+
+- type: entity
+  id: {DetachTestGrandParentOrgan}
+  components:
+  - type: Organ
+  - type: ParentOrgan
+  - type: ChildOrgan
+
+- type: entity
+  id: {DetachTestRootOrgan}
+  components:
+  - type: Organ
+  - type: ParentOrgan
+  - type: ChildOrgan
+  - type: DetachableOrgan
+    detachedBody: DetachTestNewBody
+
+- type: entity
+  id: {DetachTestChildOrgan}
+  components:
+  - type: Organ
+  - type: ChildOrgan
+
+- type: entity
+  id: {DetachTestSiblingOrgan}
+  components:
+  - type: Organ
+  - type: ChildOrgan
+";
+
+    [SidedDependency(Side.Server)] private SharedContainerSystem _container = default!;
+    [SidedDependency(Side.Server)] private OrganRelationSystem _organRelation = default!;
+    [SidedDependency(Side.Server)] private DetachableOrganSystem _detachableOrgan = default!;
+
+    [Test]
+    [RunOnSide(Side.Server)]
+    public void Detach()
+    {
+        var oldBody = SSpawn(DetachTestOldBody);
+        var oldBodyContainer = _container.GetContainer(oldBody, BodyComponent.ContainerID);
+
+        var grandParent = SSpawn(DetachTestGrandParentOrgan);
+        var root = SSpawn(DetachTestRootOrgan);
+        var child = SSpawn(DetachTestChildOrgan);
+        var sibling = SSpawn(DetachTestSiblingOrgan);
+
+        _container.Insert(grandParent, oldBodyContainer, force: true);
+        _container.Insert(root, oldBodyContainer, force: true);
+        _container.Insert(child, oldBodyContainer, force: true);
+        _container.Insert(sibling, oldBodyContainer, force: true);
+
+        _organRelation.Relate(grandParent, root);
+        _organRelation.Relate(grandParent, sibling);
+        _organRelation.Relate(root, child);
+
+        var newBody = _detachableOrgan.Detach(root);
+
+        Assert.That(newBody, Is.Not.Null);
+
+        var newBodyContained = _container.GetContainer(newBody!.Value, BodyComponent.ContainerID).ContainedEntities.ToList();
+        Assert.That(newBodyContained, Is.EquivalentTo(new[] { root, child }));
+
+        var oldBodyContained = oldBodyContainer.ContainedEntities.ToList();
+        Assert.That(oldBodyContained, Is.EquivalentTo(new[] { grandParent, sibling }));
+
+        var grandParentComp = SComp<ParentOrganComponent>(grandParent);
+        Assert.That(grandParentComp.Children, Does.Not.Contain(root));
+        Assert.That(grandParentComp.Children, Does.Contain(sibling));
+
+        Assert.That(SComp<ChildOrganComponent>(root).Parent, Is.Null);
+        Assert.That(SComp<ParentOrganComponent>(root).Children, Does.Contain(child));
+        Assert.That(SComp<ChildOrganComponent>(child).Parent, Is.EqualTo(root));
+
+        Assert.That(SComp<OrganComponent>(root).Body, Is.EqualTo(newBody));
+        Assert.That(SComp<OrganComponent>(child).Body, Is.EqualTo(newBody));
+        Assert.That(SComp<OrganComponent>(grandParent).Body, Is.EqualTo(oldBody));
+        Assert.That(SComp<OrganComponent>(sibling).Body, Is.EqualTo(oldBody));
+    }
+}
diff --git a/Content.IntegrationTests/Tests/Body/InitialBodySpawnTest.cs b/Content.IntegrationTests/Tests/Body/InitialBodySpawnTest.cs
new file mode 100644
index 0000000000..8b1b855125
--- /dev/null
+++ b/Content.IntegrationTests/Tests/Body/InitialBodySpawnTest.cs
@@ -0,0 +1,67 @@
+using System.Linq;
+using Content.IntegrationTests.Fixtures;
+using Content.IntegrationTests.Fixtures.Attributes;
+using Content.Shared.Body;
+using Robust.Shared.Containers;
+using Robust.Shared.GameObjects;
+
+namespace Content.IntegrationTests.Tests.Body;
+
+[TestFixture]
+[TestOf(typeof(InitialBodySystem))]
+public sealed class InitialBodySpawnTest : GameTest
+{
+    [TestPrototypes]
+    private const string Prototypes = @"
+- type: organCategory
+  id: InitialBodySpawnTestParent
+
+- type: organCategory
+  id: InitialBodySpawnTestChild
+
+- type: entity
+  id: InitialBodySpawnTestBody
+  components:
+  - type: Body
+  - type: InitialBody
+    organs:
+      InitialBodySpawnTestParent: InitialBodySpawnTestParentOrgan
+      InitialBodySpawnTestChild: InitialBodySpawnTestChildOrgan
+    relationships:
+      InitialBodySpawnTestParent: [InitialBodySpawnTestChild]
+
+- type: entity
+  id: InitialBodySpawnTestParentOrgan
+  components:
+  - type: Organ
+  - type: ParentOrgan
+
+- type: entity
+  id: InitialBodySpawnTestChildOrgan
+  components:
+  - type: Organ
+  - type: ChildOrgan
+";
+
+    [SidedDependency(Side.Server)] private SharedContainerSystem _container = default!;
+
+    [Test]
+    [RunOnSide(Side.Server)]
+    public void SpawningWiresUpOrganRelations()
+    {
+        var body = SSpawn("InitialBodySpawnTestBody");
+
+        var bodyContainer = _container.GetContainer(body, BodyComponent.ContainerID);
+        var contained = bodyContainer.ContainedEntities.ToList();
+        Assert.That(contained, Has.Count.EqualTo(2));
+
+        var parent = contained.Single(SEntMan.HasComponent<ParentOrganComponent>);
+        var child = contained.Single(SEntMan.HasComponent<ChildOrganComponent>);
+
+        var parentComp = SComp<ParentOrganComponent>(parent);
+        var childComp = SComp<ChildOrganComponent>(child);
+
+        Assert.That(parentComp.Children, Does.Contain(child));
+        Assert.That(childComp.Parent, Is.EqualTo(parent));
+    }
+}
diff --git a/Content.IntegrationTests/Tests/Body/InitialBodyValidationTest.cs b/Content.IntegrationTests/Tests/Body/InitialBodyValidationTest.cs
new file mode 100644
index 0000000000..851964e422
--- /dev/null
+++ b/Content.IntegrationTests/Tests/Body/InitialBodyValidationTest.cs
@@ -0,0 +1,179 @@
+using System.Collections.Generic;
+using System.Linq;
+using Content.IntegrationTests.Fixtures;
+using Content.IntegrationTests.Fixtures.Attributes;
+using Content.Shared.Body;
+using Robust.Shared.GameObjects;
+using Robust.Shared.Prototypes;
+
+namespace Content.IntegrationTests.Tests.Body;
+
+[TestFixture]
+[TestOf(typeof(InitialBodySystem))]
+public sealed class InitialBodyValidationTest : GameTest
+{
+    [SidedDependency(Side.Server)] private IComponentFactory _componentFactory = default!;
+    [SidedDependency(Side.Server)] private IPrototypeManager _prototype = default!;
+
+    [Test]
+    [RunOnSide(Side.Server)]
+    public void RelatedOrgansCanBeRelated()
+    {
+        using var scope = Assert.EnterMultipleScope();
+
+        foreach (var proto in _prototype.EnumeratePrototypes<EntityPrototype>())
+        {
+            if (proto.Abstract || Pair.IsTestEntityPrototype(proto.ID))
+                continue;
+
+            if (!proto.TryComp<InitialBodyComponent>(out var initial, _componentFactory))
+                continue;
+
+            if (initial.Relationships is not { } relationships)
+                continue;
+
+            var organs = initial.Organs;
+            foreach (var (parent, children) in relationships)
+            {
+                if (!organs.TryGetValue(parent, out var parentProtoId))
+                    continue;
+
+                var parentProto = _prototype.Index(parentProtoId);
+                if (!parentProto.HasComp<ParentOrganComponent>(_componentFactory))
+                {
+                    Assert.Fail($"{proto.ID}'s parent organ {parent} {parentProtoId} is missing {nameof(ParentOrganComponent)}");
+                }
+
+                foreach (var child in children)
+                {
+                    if (!organs.TryGetValue(child, out var childProtoId))
+                        continue;
+
+                    var childProto = _prototype.Index(childProtoId);
+                    if (!childProto.HasComp<ChildOrganComponent>(_componentFactory))
+                    {
+                        Assert.Fail($"{proto.ID}'s child organ {child} {childProtoId} (child of {parent} {parentProtoId}) is missing {nameof(ChildOrganComponent)}");
+                    }
+                }
+            }
+        }
+    }
+
+    [Test]
+    [RunOnSide(Side.Server)]
+    public void NoMultipleParents()
+    {
+        using var scope = Assert.EnterMultipleScope();
+
+        foreach (var proto in _prototype.EnumeratePrototypes<EntityPrototype>())
+        {
+            if (proto.Abstract || Pair.IsTestEntityPrototype(proto.ID))
+                continue;
+
+            if (!proto.TryComp<InitialBodyComponent>(out var initial, _componentFactory))
+                continue;
+
+            if (initial.Relationships is not { } relationships)
+                continue;
+
+            var parentOf = new Dictionary<ProtoId<OrganCategoryPrototype>, ProtoId<OrganCategoryPrototype>>();
+            foreach (var (parent, children) in relationships)
+            {
+                foreach (var child in children)
+                {
+                    if (parentOf.TryGetValue(child, out var existingParent))
+                    {
+                        Assert.Fail($"{proto.ID}'s organ category {child} is claimed as a child by both {existingParent} and {parent}");
+                    }
+
+                    parentOf[child] = parent;
+                }
+            }
+        }
+    }
+
+    [Test]
+    [RunOnSide(Side.Server)]
+    public void InternalChildOrgansAreNotDetachable()
+    {
+        using var scope = Assert.EnterMultipleScope();
+
+        foreach (var proto in _prototype.EnumeratePrototypes<EntityPrototype>())
+        {
+            if (proto.Abstract || Pair.IsTestEntityPrototype(proto.ID))
+                continue;
+
+            if (!proto.HasComp<InternalChildOrganComponent>(_componentFactory))
+                continue;
+
+            if (proto.HasComp<DetachableOrganComponent>(_componentFactory))
+            {
+                Assert.Fail($"{proto.ID} has both {nameof(InternalChildOrganComponent)} and {nameof(DetachableOrganComponent)}. Pick a lane, make your organs internal or detachable, but not both.");
+            }
+        }
+    }
+
+    [Test]
+    [RunOnSide(Side.Server)]
+    public void NoCyclicalRelationships()
+    {
+        using var scope = Assert.EnterMultipleScope();
+
+        foreach (var proto in _prototype.EnumeratePrototypes<EntityPrototype>())
+        {
+            if (proto.Abstract || Pair.IsTestEntityPrototype(proto.ID))
+                continue;
+
+            if (!proto.TryComp<InitialBodyComponent>(out var initial, _componentFactory))
+                continue;
+
+            if (initial.Relationships is not { } relationships)
+                continue;
+
+            var visited = new HashSet<ProtoId<OrganCategoryPrototype>>();
+            var stack = new List<ProtoId<OrganCategoryPrototype>>();
+
+            foreach (var parent in relationships.Keys)
+            {
+                if (TryFindCycle(parent, relationships, visited, stack, out var cycle))
+                {
+                    Assert.Fail($"{proto.ID} has a cycle in its InitialBodyComponent relationships: {string.Join(" -> ", cycle)}");
+                }
+            }
+        }
+    }
+
+    private static bool TryFindCycle(
+        ProtoId<OrganCategoryPrototype> node,
+        Dictionary<ProtoId<OrganCategoryPrototype>, HashSet<ProtoId<OrganCategoryPrototype>>> relationships,
+        HashSet<ProtoId<OrganCategoryPrototype>> visited,
+        List<ProtoId<OrganCategoryPrototype>> stack,
+        out List<ProtoId<OrganCategoryPrototype>> cycle)
+    {
+        if (stack.Contains(node))
+        {
+            var start = stack.IndexOf(node);
+            cycle = stack.Skip(start).Append(node).ToList();
+            return true;
+        }
+
+        cycle = new List<ProtoId<OrganCategoryPrototype>>();
+
+        if (!visited.Add(node))
+            return false;
+
+        if (!relationships.TryGetValue(node, out var children))
+            return false;
+
+        stack.Add(node);
+
+        foreach (var child in children)
+        {
+            if (TryFindCycle(child, relationships, visited, stack, out cycle))
+                return true;
+        }
+
+        stack.RemoveAt(stack.Count - 1);
+        return false;
+    }
+}
diff --git a/Content.IntegrationTests/Tests/Body/OrganRelationSystemTest.cs b/Content.IntegrationTests/Tests/Body/OrganRelationSystemTest.cs
new file mode 100644
index 0000000000..ee012f9815
--- /dev/null
+++ b/Content.IntegrationTests/Tests/Body/OrganRelationSystemTest.cs
@@ -0,0 +1,93 @@
+using System.Linq;
+using Content.IntegrationTests.Fixtures;
+using Content.IntegrationTests.Fixtures.Attributes;
+using Content.Shared.Body;
+using Robust.Shared.GameObjects;
+using Robust.Shared.Map;
+
+namespace Content.IntegrationTests.Tests.Body;
+
+[TestFixture]
+[TestOf(typeof(OrganRelationSystem))]
+public sealed class OrganRelationSystemTest : GameTest
+{
+    [TestPrototypes]
+    private const string Prototypes = @"
+- type: entity
+  id: OrganRelationTestOrgan
+  components:
+  - type: Organ
+  - type: ParentOrgan
+  - type: ChildOrgan
+";
+
+    [SidedDependency(Side.Server)] private OrganRelationSystem _organRelation = default!;
+
+    [Test]
+    [RunOnSide(Side.Server)]
+    public void RelateAndOrphan()
+    {
+        var parent = SSpawn("OrganRelationTestOrgan");
+        var child = SSpawn("OrganRelationTestOrgan");
+
+        _organRelation.Relate(parent, child);
+
+        var parentComp = SComp<ParentOrganComponent>(parent);
+        var childComp = SComp<ChildOrganComponent>(child);
+
+        Assert.That(parentComp.Children, Does.Contain(child));
+        Assert.That(childComp.Parent, Is.EqualTo(parent));
+
+        _organRelation.Orphan(child);
+
+        Assert.That(parentComp.Children, Does.Not.Contain(child));
+        Assert.That(childComp.Parent, Is.Null);
+    }
+
+    [Test]
+    [RunOnSide(Side.Server)]
+    public void Traversal()
+    {
+        var grandParent = SSpawn("OrganRelationTestOrgan");
+        var parent = SSpawn("OrganRelationTestOrgan");
+        var child = SSpawn("OrganRelationTestOrgan");
+
+        _organRelation.Relate(grandParent, parent);
+        _organRelation.Relate(parent, child);
+
+        var allChildren = _organRelation.AllChildren(grandParent).Select(e => e.Owner).ToList();
+        Assert.That(allChildren, Is.EquivalentTo(new[] { parent, child }));
+
+        var allParents = _organRelation.AllParents(child).Select(e => e.Owner).ToList();
+        Assert.That(allParents, Is.EquivalentTo(new[] { parent, grandParent }));
+    }
+
+    [Test]
+    [RunOnSide(Side.Server)]
+    public void ParentDeletion()
+    {
+        var parent = SSpawn("OrganRelationTestOrgan");
+        var child = SSpawn("OrganRelationTestOrgan");
+
+        _organRelation.Relate(parent, child);
+
+        SDeleteNow(parent);
+
+        Assert.That(SEntMan.Deleted(child), Is.False);
+        Assert.That(SComp<ChildOrganComponent>(child).Parent, Is.Null);
+    }
+
+    [Test]
+    [RunOnSide(Side.Server)]
+    public void ChildDeletion()
+    {
+        var parent = SSpawn("OrganRelationTestOrgan");
+        var child = SSpawn("OrganRelationTestOrgan");
+
+        _organRelation.Relate(parent, child);
+
+        SDeleteNow(child);
+
+        Assert.That(SComp<ParentOrganComponent>(parent).Children, Does.Not.Contain(child));
+    }
+}
diff --git a/Content.IntegrationTests/Tests/Sprite/ItemSpriteTest.cs b/Content.IntegrationTests/Tests/Sprite/ItemSpriteTest.cs
index ca667f2e7a..4c2f0be60e 100644
--- a/Content.IntegrationTests/Tests/Sprite/ItemSpriteTest.cs
+++ b/Content.IntegrationTests/Tests/Sprite/ItemSpriteTest.cs
@@ -29,7 +29,8 @@ public sealed class PrototypeSaveTest : GameTest
     {
         // The only prototypes that should get ignored are those that REQUIRE setup to get a sprite. At that point it is
         // the responsibility of the spawner to ensure that a valid sprite is set.
-        "VirtualItem"
+        "VirtualItem",
+        "DetachedBody"
     };
 
     [Test]
diff --git a/Content.Server/Body/BodyCommand.cs b/Content.Server/Body/BodyCommand.cs
new file mode 100644
index 0000000000..6e9fe5b838
--- /dev/null
+++ b/Content.Server/Body/BodyCommand.cs
@@ -0,0 +1,42 @@
+using System.Linq;
+using Content.Server.Administration;
+using Content.Shared.Administration;
+using Content.Shared.Body;
+using Robust.Shared.Containers;
+using Robust.Shared.Toolshed;
+
+namespace Content.Server.Body;
+
+[ToolshedCommand, AdminCommand(AdminFlags.Debug)]
+public sealed class BodyCommand : ToolshedCommand
+{
+    private SharedContainerSystem? _container;
+
+    [CommandImplementation("insert")]
+    public void Insert([PipedArgument] EntityUid body, EntityUid organ)
+    {
+        _container ??= GetSys<SharedContainerSystem>();
+
+        if (!_container.TryGetContainer(body, BodyComponent.ContainerID, out var container))
+            return;
+
+        _container.Insert(organ, container, force: true);
+    }
+
+    [CommandImplementation("organs")]
+    public IEnumerable<EntityUid> Organs([PipedArgument] EntityUid body)
+    {
+        _container ??= GetSys<SharedContainerSystem>();
+
+        if (!_container.TryGetContainer(body, BodyComponent.ContainerID, out var container))
+            return Enumerable.Empty<EntityUid>();
+
+        return container.ContainedEntities.ToList();
+    }
+
+    [CommandImplementation("organs")]
+    public IEnumerable<EntityUid> Organs([PipedArgument] IEnumerable<EntityUid> body)
+    {
+        return body.SelectMany(Organs);
+    }
+}
diff --git a/Content.Server/Body/OrganCommand.cs b/Content.Server/Body/OrganCommand.cs
new file mode 100644
index 0000000000..e791783cf6
--- /dev/null
+++ b/Content.Server/Body/OrganCommand.cs
@@ -0,0 +1,112 @@
+using System.Linq;
+using Content.Server.Administration;
+using Content.Shared.Administration;
+using Content.Shared.Body;
+using Robust.Shared.Containers;
+using Robust.Shared.Prototypes;
+using Robust.Shared.Toolshed;
+
+namespace Content.Server.Body;
+
+[ToolshedCommand, AdminCommand(AdminFlags.Debug)]
+public sealed class OrganCommand : ToolshedCommand
+{
+    private DetachableOrganSystem? _detachableOrgan;
+    private SharedContainerSystem? _container;
+    private OrganRelationSystem? _organRelation;
+
+    [CommandImplementation("parent")]
+    public EntityUid? Parent([PipedArgument] EntityUid child)
+    {
+        if (!TryComp<ChildOrganComponent>(child, out var childOrgan))
+            return null;
+
+        return childOrgan.Parent;
+    }
+
+    [CommandImplementation("parent")]
+    public IEnumerable<EntityUid?> Parent([PipedArgument] IEnumerable<EntityUid> children)
+    {
+        return children.Select(Parent);
+    }
+
+    [CommandImplementation("children")]
+    public IEnumerable<EntityUid> Children([PipedArgument] EntityUid parent)
+    {
+        if (!TryComp<ParentOrganComponent>(parent, out var parentOrgan))
+            yield break;
+
+        foreach (var child in parentOrgan.Children)
+        {
+            yield return child;
+        }
+    }
+
+    [CommandImplementation("children")]
+    public IEnumerable<EntityUid> Children([PipedArgument] IEnumerable<EntityUid> parents)
+    {
+        return parents.SelectMany(Children);
+    }
+
+    [CommandImplementation("detach")]
+    public EntityUid? Detach([PipedArgument] EntityUid organ)
+    {
+        _detachableOrgan ??= GetSys<DetachableOrganSystem>();
+        return _detachableOrgan.Detach(organ);
+    }
+
+    [CommandImplementation("detach")]
+    public IEnumerable<EntityUid?> Detach([PipedArgument] IEnumerable<EntityUid> organs)
+    {
+        return organs.Select(Detach);
+    }
+
+    [CommandImplementation("attach")]
+    public void Attach([PipedArgument] EntityUid parent, EntityUid child)
+    {
+        _container ??= GetSys<SharedContainerSystem>();
+        _organRelation ??= GetSys<OrganRelationSystem>();
+
+        if (!TryComp<ParentOrganComponent>(parent, out var parentOrgan) ||
+            !TryComp<ChildOrganComponent>(child, out var childOrgan) ||
+            !TryComp<OrganComponent>(parent, out var parentOrganComponent) ||
+            parentOrganComponent.Body is not { } body)
+            return;
+
+        if (!_container.TryGetContainer(body, BodyComponent.ContainerID, out var container))
+            return;
+
+        _container.Insert(child, container, force: true);
+        _organRelation.Relate((parent, parentOrgan), (child, childOrgan));
+    }
+
+    [CommandImplementation("attach")]
+    public void Attach([PipedArgument] IEnumerable<EntityUid> parents, EntityUid child)
+    {
+        foreach (var parent in parents)
+        {
+            Attach(parent, child);
+        }
+    }
+
+    [CommandImplementation("is")]
+    public bool Is([PipedArgument] EntityUid organ, ProtoId<OrganCategoryPrototype> category)
+    {
+        if (!TryComp<OrganComponent>(organ, out var organComp))
+            return false;
+
+        return organComp.Category == category;
+    }
+
+    [CommandImplementation("is")]
+    public IEnumerable<bool> Is([PipedArgument] IEnumerable<EntityUid> organs, ProtoId<OrganCategoryPrototype> category)
+    {
+        return organs.Select(it => Is(it, category));
+    }
+
+    [CommandImplementation("of_type")]
+    public IEnumerable<EntityUid> Typed([PipedArgument] IEnumerable<EntityUid> organs, ProtoId<OrganCategoryPrototype> category)
+    {
+        return organs.Where(it => Is(it, category));
+    }
+}
diff --git a/Content.Shared/Body/ChildOrganComponent.cs b/Content.Shared/Body/ChildOrganComponent.cs
new file mode 100644
index 0000000000..815f8d3423
--- /dev/null
+++ b/Content.Shared/Body/ChildOrganComponent.cs
@@ -0,0 +1,17 @@
+using Robust.Shared.GameStates;
+
+namespace Content.Shared.Body;
+
+/// <summary>
+/// An organ that can be a child to a parent organ within a body.
+/// </summary>
+[RegisterComponent, NetworkedComponent, AutoGenerateComponentState]
+[Access(typeof(OrganRelationSystem))]
+public sealed partial class ChildOrganComponent : Component
+{
+    /// <summary>
+    /// The current organ that's a parent to this one, if any
+    /// </summary>
+    [DataField, AutoNetworkedField]
+    public EntityUid? Parent;
+}
diff --git a/Content.Shared/Body/DetachableOrganComponent.cs b/Content.Shared/Body/DetachableOrganComponent.cs
new file mode 100644
index 0000000000..9cd0af4115
--- /dev/null
+++ b/Content.Shared/Body/DetachableOrganComponent.cs
@@ -0,0 +1,18 @@
+using Robust.Shared.GameStates;
+using Robust.Shared.Prototypes;
+
+namespace Content.Shared.Body;
+
+/// <summary>
+/// An organ that can be detached with all of its children into a new body
+/// </summary>
+[RegisterComponent, NetworkedComponent]
+[Access(typeof(DetachableOrganSystem))]
+public sealed partial class DetachableOrganComponent : Component
+{
+    /// <summary>
+    /// The body to spawn upon detaching
+    /// </summary>
+    [DataField(required: true)]
+    public EntProtoId DetachedBody;
+}
diff --git a/Content.Shared/Body/DetachableOrganSystem.cs b/Content.Shared/Body/DetachableOrganSystem.cs
new file mode 100644
index 0000000000..ce1d720acc
--- /dev/null
+++ b/Content.Shared/Body/DetachableOrganSystem.cs
@@ -0,0 +1,52 @@
+using Content.Shared.Body;
+using JetBrains.Annotations;
+using Robust.Shared.Containers;
+using Robust.Shared.Network;
+
+namespace Content.Shared.Body;
+
+public sealed partial class DetachableOrganSystem : EntitySystem
+{
+    [Dependency] private EntityQuery<DetachableOrganComponent> _detachableOrgan;
+    [Dependency] private EntityQuery<OrganComponent> _organ;
+    [Dependency] private OrganRelationSystem _organRelation = default!;
+    [Dependency] private SharedContainerSystem _container = default!;
+
+    /// <summary>
+    /// Detaches an organ from its containing body.
+    /// </summary>
+    /// <param name="organ">The organ to detach</param>
+    /// <returns>The body that spawned when this organ was detached</returns>
+    [PublicAPI]
+    public EntityUid? Detach(Entity<DetachableOrganComponent?> organ)
+    {
+        if (!_detachableOrgan.Resolve(organ, ref organ.Comp) || !_organ.TryComp(organ, out var organComp) || organComp.Body is not { } oldBody)
+            return null;
+
+        _organRelation.Orphan(organ.Owner);
+        var body = PredictedSpawnNextToOrDrop(organ.Comp.DetachedBody, oldBody);
+
+        if (!_container.TryGetContainer(body, BodyComponent.ContainerID, out var container))
+        {
+            Log.Error($"Entity {ToPrettyString(body)} relied on by {nameof(DetachableOrganComponent)} on {ToPrettyString(organ)} is missing a container ({BodyComponent.ContainerID}).");
+            Del(body);
+            return null;
+        }
+
+        if (!_container.Insert(organ.Owner, container, force: true))
+        {
+            Log.Error($"{ToPrettyString(organ)} could not be transferred to new body {ToPrettyString(body)}.");
+        }
+
+        foreach (var child in _organRelation.AllChildren(organ.Owner))
+        {
+            if (!_container.Insert(child.Owner, container, force: true))
+            {
+                Log.Error($"{ToPrettyString(child)} could not be transferred to new body {ToPrettyString(body)}.");
+                _organRelation.Orphan(child.AsNullable());
+            }
+        }
+
+        return body;
+    }
+}
diff --git a/Content.Shared/Body/InitialBodyComponent.cs b/Content.Shared/Body/InitialBodyComponent.cs
index a27e5c092c..70326ea7d4 100644
--- a/Content.Shared/Body/InitialBodyComponent.cs
+++ b/Content.Shared/Body/InitialBodyComponent.cs
@@ -15,4 +15,10 @@ public sealed partial class InitialBodyComponent : Component
     /// </summary>
     [DataField(required: true)]
     public Dictionary<ProtoId<OrganCategoryPrototype>, EntProtoId<OrganComponent>> Organs;
+
+    /// <summary>
+    /// Organ relationships, based on their categories. Keys are parents to their values.
+    /// </summary>
+    [DataField]
+    public Dictionary<ProtoId<OrganCategoryPrototype>, HashSet<ProtoId<OrganCategoryPrototype>>>? Relationships;
 }
diff --git a/Content.Shared/Body/InitialBodySystem.cs b/Content.Shared/Body/InitialBodySystem.cs
index 6ac8066e54..5df762e495 100644
--- a/Content.Shared/Body/InitialBodySystem.cs
+++ b/Content.Shared/Body/InitialBodySystem.cs
@@ -1,12 +1,14 @@
 using System.Numerics;
 using Robust.Shared.Containers;
 using Robust.Shared.Map;
+using Robust.Shared.Prototypes;
 
 namespace Content.Shared.Body;
 
 public sealed partial class InitialBodySystem : EntitySystem
 {
     [Dependency] private SharedContainerSystem _container = default!;
+    [Dependency] private OrganRelationSystem _organRelation = default!;
 
     public override void Initialize()
     {
@@ -31,8 +33,9 @@ public sealed partial class InitialBodySystem : EntitySystem
 
         var xform = Transform(ent);
         var coords = new EntityCoordinates(ent, Vector2.Zero);
+        var spawned = new Dictionary<ProtoId<OrganCategoryPrototype>, EntityUid>();
 
-        foreach (var proto in ent.Comp.Organs.Values)
+        foreach (var (part, proto) in ent.Comp.Organs)
         {
             // TODO: When e#6192 is merged replace this all with TrySpawnInContainer...
             var spawn = Spawn(proto, coords);
@@ -41,6 +44,26 @@ public sealed partial class InitialBodySystem : EntitySystem
             {
                 Log.Error($"Entity {ToPrettyString(ent)} with a {nameof(InitialBodyComponent)} failed to insert an entity: {ToPrettyString(spawn)}.\n");
                 Del(spawn);
+                continue;
+            }
+
+            spawned[part] = spawn;
+        }
+
+        if (ent.Comp.Relationships is null)
+            return;
+
+        foreach (var (partId, parentUid) in spawned)
+        {
+            if (!ent.Comp.Relationships.TryGetValue(partId, out var children))
+                continue;
+
+            foreach (var childId in children)
+            {
+                if (!spawned.TryGetValue(childId, out var childUid))
+                    continue;
+
+                _organRelation.Relate(parentUid, childUid);
             }
         }
     }
diff --git a/Content.Shared/Body/InternalChildOrganComponent.cs b/Content.Shared/Body/InternalChildOrganComponent.cs
new file mode 100644
index 0000000000..0f3c9348ef
--- /dev/null
+++ b/Content.Shared/Body/InternalChildOrganComponent.cs
@@ -0,0 +1,9 @@
+using Robust.Shared.GameStates;
+
+namespace Content.Shared.Body;
+
+/// <summary>
+/// Marker components for child organs that are considered "internal" to their parent. e.g. kidneys are internal to a torso, but an arm isn't.
+/// </summary>
+[RegisterComponent, NetworkedComponent]
+public sealed partial class InternalChildOrganComponent : Component;
diff --git a/Content.Shared/Body/OrganRelationSystem.cs b/Content.Shared/Body/OrganRelationSystem.cs
new file mode 100644
index 0000000000..d5236277e8
--- /dev/null
+++ b/Content.Shared/Body/OrganRelationSystem.cs
@@ -0,0 +1,120 @@
+using JetBrains.Annotations;
+using Robust.Shared.Utility;
+
+namespace Content.Shared.Body;
+
+public sealed partial class OrganRelationSystem : EntitySystem
+{
+    [Dependency] private EntityQuery<ChildOrganComponent> _child;
+    [Dependency] private EntityQuery<ParentOrganComponent> _parent;
+
+    public override void Initialize()
+    {
+        base.Initialize();
+
+        SubscribeLocalEvent<ParentOrganComponent, ComponentShutdown>(OnParentShutdown);
+        SubscribeLocalEvent<ChildOrganComponent, ComponentShutdown>(OnChildShutdown);
+    }
+
+    private void OnChildShutdown(Entity<ChildOrganComponent> ent, ref ComponentShutdown args)
+    {
+        if (ent.Comp.Parent is not { } parentUid)
+            return;
+
+        var parentComp = _parent.Comp(parentUid);
+        parentComp.Children.Remove(ent);
+        Dirty(parentUid, parentComp);
+    }
+
+    private void OnParentShutdown(Entity<ParentOrganComponent> ent, ref ComponentShutdown args)
+    {
+        if (ent.Comp.Children.Count == 0)
+            return;
+
+        foreach (var childUid in ent.Comp.Children)
+        {
+            var childComp = _child.Comp(childUid);
+            childComp.Parent = null;
+
+            Dirty(childUid, childComp);
+        }
+    }
+
+    /// <summary>
+    /// Associates a parent organ and a child organ.
+    /// </summary>
+    [PublicAPI]
+    public void Relate(Entity<ParentOrganComponent?> parent, Entity<ChildOrganComponent?> child)
+    {
+        if (!_parent.Resolve(parent, ref parent.Comp) || !_child.Resolve(child, ref child.Comp))
+            return;
+
+        DebugTools.Assert(child.Comp.Parent == null);
+
+        parent.Comp.Children.Add(child);
+        Dirty(parent, parent.Comp);
+
+        child.Comp.Parent = parent;
+        Dirty(child, child.Comp);
+    }
+
+    /// <summary>
+    /// Breaks the relationship between a child orphan and its parent.
+    /// </summary>
+    [PublicAPI]
+    public void Orphan(Entity<ChildOrganComponent?> child)
+    {
+        if (!_child.Resolve(child, ref child.Comp))
+            return;
+
+        if (child.Comp.Parent is not { } parentUid)
+            return;
+
+        child.Comp.Parent = null;
+        Dirty(child, child.Comp);
+
+        var parentComp = _parent.Comp(parentUid);
+        parentComp.Children.Remove(child);
+        Dirty(parentUid, parentComp);
+    }
+
+    /// <summary>
+    /// Enumerates all parents of a child organ recursively.
+    /// </summary>
+    [PublicAPI]
+    public IEnumerable<Entity<ParentOrganComponent>> AllParents(Entity<ChildOrganComponent?> child)
+    {
+        if (!_child.Resolve(child, ref child.Comp))
+            yield break;
+
+        while (child.Comp?.Parent is { } parent)
+        {
+            yield return (parent, _parent.Comp(parent));
+
+            if (!_child.TryGetComponent(parent, out var parentChild))
+                yield break;
+
+            child = (parent, parentChild);
+        }
+    }
+
+    /// <summary>
+    /// Enumerates all children of a parent organ recursively.
+    /// </summary>
+    [PublicAPI]
+    public IEnumerable<Entity<ChildOrganComponent>> AllChildren(Entity<ParentOrganComponent?> parent)
+    {
+        if (!_parent.Resolve(parent, ref parent.Comp, false))
+            yield break;
+
+        foreach (var child in parent.Comp.Children)
+        {
+            yield return (child, _child.Comp(child));
+
+            foreach (var childChild in AllChildren(child))
+            {
+                yield return childChild;
+            }
+        }
+    }
+}
diff --git a/Content.Shared/Body/ParentOrganComponent.cs b/Content.Shared/Body/ParentOrganComponent.cs
new file mode 100644
index 0000000000..e82fa70574
--- /dev/null
+++ b/Content.Shared/Body/ParentOrganComponent.cs
@@ -0,0 +1,17 @@
+using Robust.Shared.GameStates;
+
+namespace Content.Shared.Body;
+
+/// <summary>
+/// An organ that can be a parent to other organs.
+/// </summary>
+[RegisterComponent, NetworkedComponent, AutoGenerateComponentState]
+[Access(typeof(OrganRelationSystem))]
+public sealed partial class ParentOrganComponent : Component
+{
+    /// <summary>
+    /// The current set of child organs parented to this one.
+    /// </summary>
+    [DataField, AutoNetworkedField]
+    public HashSet<EntityUid> Children = new();
+}
diff --git a/Resources/Locale/en-US/body/commands.ftl b/Resources/Locale/en-US/body/commands.ftl
new file mode 100644
index 0000000000..e170e7e62a
--- /dev/null
+++ b/Resources/Locale/en-US/body/commands.ftl
@@ -0,0 +1,23 @@
+command-description-body-insert =
+    Inserts the given organ into the body.
+
+command-description-body-organs =
+    Returns all organs contained within the body.
+
+command-description-organ-parent =
+    Returns the parent of the organ.
+
+command-description-organ-children =
+    Returns the children of the organ.
+
+command-description-organ-detach =
+    (DEBUG ONLY) Detaches an organ from its current body into a detached body.
+
+command-description-organ-attach =
+    Attaches an organ to another organ.
+
+command-description-organ-is =
+    Returns if an organ is the given type.
+
+command-description-organ-of_type =
+    Filters to organs of the given type.
diff --git a/Resources/Prototypes/Body/base_organs.yml b/Resources/Prototypes/Body/base_organs.yml
index f77e83e75a..0db5199615 100644
--- a/Resources/Prototypes/Body/base_organs.yml
+++ b/Resources/Prototypes/Body/base_organs.yml
@@ -43,7 +43,10 @@
     - Meat
 
 - type: entity
-  parent: OrganBase
+  parent:
+  - OrganBase
+  - OrganBaseParent
+  - OrganBaseChildExternal
   id: OrganBaseTorso
   name: torso
   abstract: true
@@ -68,7 +71,10 @@
       - Special
 
 - type: entity
-  parent: OrganBase
+  parent:
+  - OrganBase
+  - OrganBaseParent
+  - OrganBaseChildExternal
   id: OrganBaseHead
   name: head
   abstract: true
@@ -95,7 +101,10 @@
       - HeadTop
 
 - type: entity
-  parent: OrganBase
+  parent:
+  - OrganBase
+  - OrganBaseParent
+  - OrganBaseChildExternal
   id: OrganBaseArmLeft
   name: left arm
   abstract: true
@@ -114,7 +123,10 @@
       - LArm
 
 - type: entity
-  parent: OrganBase
+  parent:
+  - OrganBase
+  - OrganBaseParent
+  - OrganBaseChildExternal
   id: OrganBaseArmRight
   name: right arm
   abstract: true
@@ -133,7 +145,9 @@
       - RArm
 
 - type: entity
-  parent: OrganBase
+  parent:
+  - OrganBase
+  - OrganBaseChildExternal
   id: OrganBaseHandLeft
   name: left hand
   abstract: true
@@ -156,7 +170,9 @@
       - LHand
 
 - type: entity
-  parent: OrganBase
+  parent:
+  - OrganBase
+  - OrganBaseChildExternal
   id: OrganBaseHandRight
   name: right hand
   abstract: true
@@ -179,7 +195,10 @@
       - RHand
 
 - type: entity
-  parent: OrganBase
+  parent:
+  - OrganBase
+  - OrganBaseParent
+  - OrganBaseChildExternal
   id: OrganBaseLegLeft
   name: left leg
   abstract: true
@@ -198,7 +217,10 @@
       - LLeg
 
 - type: entity
-  parent: OrganBase
+  parent:
+  - OrganBase
+  - OrganBaseParent
+  - OrganBaseChildExternal
   id: OrganBaseLegRight
   name: right leg
   abstract: true
@@ -217,7 +239,9 @@
       - RLeg
 
 - type: entity
-  parent: OrganBase
+  parent:
+  - OrganBase
+  - OrganBaseChildExternal
   id: OrganBaseFootLeft
   name: left foot
   abstract: true
@@ -236,7 +260,9 @@
       - LFoot
 
 - type: entity
-  parent: OrganBase
+  parent:
+  - OrganBase
+  - OrganBaseChildExternal
   id: OrganBaseFootRight
   name: right foot
   abstract: true
@@ -255,7 +281,9 @@
       - RFoot
 
 - type: entity
-  parent: OrganBase
+  parent:
+  - OrganBase
+  - OrganBaseChildInternal
   id: OrganBaseBrain
   name: brain
   abstract: true
@@ -288,7 +316,9 @@
       Taco: Brain
 
 - type: entity
-  parent: OrganBase
+  parent:
+  - OrganBase
+  - OrganBaseChildInternal
   id: OrganBaseEyes
   name: eyes
   abstract: true
@@ -311,7 +341,9 @@
       - Eyes
 
 - type: entity
-  parent: OrganBase
+  parent:
+  - OrganBase
+  - OrganBaseChildInternal
   id: OrganBaseTongue
   name: tongue
   abstract: true
@@ -324,7 +356,9 @@
     - state: tongue
 
 - type: entity
-  parent: OrganBase
+  parent:
+  - OrganBase
+  - OrganBaseChildInternal
   id: OrganBaseAppendix
   name: appendix
   abstract: true
@@ -337,7 +371,9 @@
     - state: appendix
 
 - type: entity
-  parent: OrganBase
+  parent:
+  - OrganBase
+  - OrganBaseChildInternal
   id: OrganBaseEars
   name: ears
   abstract: true
@@ -350,7 +386,9 @@
     - state: ears
 
 - type: entity
-  parent: OrganBase
+  parent:
+  - OrganBase
+  - OrganBaseChildInternal
   id: OrganBaseLungs
   name: lungs
   abstract: true
@@ -383,7 +421,9 @@
       canReact: false
 
 - type: entity
-  parent: OrganBase
+  parent:
+  - OrganBase
+  - OrganBaseChildInternal
   id: OrganBaseHeart
   name: heart
   abstract: true
@@ -399,7 +439,9 @@
     stages: [ Bloodstream ]
 
 - type: entity
-  parent: OrganBase
+  parent:
+  - OrganBase
+  - OrganBaseChildInternal
   id: OrganBaseStomach
   name: stomach
   abstract: true
@@ -431,7 +473,9 @@
       maxVol: 150 # 1.25 liters which is average for a human
 
 - type: entity
-  parent: OrganBase
+  parent:
+  - OrganBase
+  - OrganBaseChildInternal
   id: OrganBaseLiver
   name: liver
   abstract: true
@@ -449,7 +493,9 @@
     stages: [ Metabolites ]
 
 - type: entity
-  parent: OrganBase
+  parent:
+  - OrganBase
+  - OrganBaseChildInternal
   id: OrganBaseKidneys
   name: kidneys
   abstract: true
@@ -498,3 +544,26 @@
     sexStateOverrides:
       Male: torso_m
       Female: torso_f
+
+- type: entity
+  abstract: true
+  id: OrganBaseParent
+  components:
+  - type: ParentOrgan
+  - type: DetachableOrgan
+    detachedBody: DetachedBody
+
+- type: entity
+  abstract: true
+  id: OrganBaseChildExternal
+  components:
+  - type: ChildOrgan
+  - type: DetachableOrgan
+    detachedBody: DetachedBody
+
+- type: entity
+  abstract: true
+  id: OrganBaseChildInternal
+  components:
+  - type: ChildOrgan
+  - type: InternalChildOrgan
diff --git a/Resources/Prototypes/Body/detached.yml b/Resources/Prototypes/Body/detached.yml
new file mode 100644
index 0000000000..65e370eb8c
--- /dev/null
+++ b/Resources/Prototypes/Body/detached.yml
@@ -0,0 +1,15 @@
+- type: entity
+  parent:
+  - BaseSpeciesLayers
+  id: DetachedBody
+  save: false
+  components:
+  - type: Clickable
+  - type: Body
+  - type: VisualBody
+  - type: ContainerContainer
+  - type: Appearance
+  - type: HideableHumanoidLayers
+  - type: Item
+  - type: InteractionOutline
+  - type: InputMover
diff --git a/Resources/Prototypes/Body/species_appearance.yml b/Resources/Prototypes/Body/species_appearance.yml
index e70b6abb38..574fdbf820 100644
--- a/Resources/Prototypes/Body/species_appearance.yml
+++ b/Resources/Prototypes/Body/species_appearance.yml
@@ -87,3 +87,11 @@
         type: HumanoidMarkingModifierBoundUserInterface
       enum.StrippingUiKey.Key:
         type: StrippableBoundUserInterface
+  - type: InitialBody
+    relationships:
+      Torso: [Head, ArmLeft, ArmRight, LegLeft, LegRight, Appendix, Lungs, Heart, Stomach, Liver, Kidneys]
+      Head: [Brain, Eyes, Tongue, Ears]
+      ArmLeft: [HandLeft]
+      ArmRight: [HandRight]
+      LegLeft: [FootLeft]
+      LegRight: [FootRight]